283 research outputs found

    Measurement of radiated underwater noise from a small research vessel in shallow water

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    The impact of man-made underwater noise on the marine environment has in recent years received increased attention from regulatory authorities, as evidenced by its inclusion in the Marine Strategy Framework Directive (MSFD) of the European Union (EU). Radiated underwater noise from ships, primarily resulting from propeller cavitation, has for many years been understood to be one of the major contributors to ambient ocean noise. Civilian research in this area has to date been relatively limited; standards covering the measurement of radiated noise from ships in deep water and data analysis procedures have only recently been published by national and international standards institutes. Less attention has so far been paid to the measurement of radiated noise from ships in shallow water environments. This is of interest as shallow water areas are more likely to be used by civilian researchers due to the logistical problems involved in undertaking trials in deep water. The issue of shipping noise has been identified as one requiring further research, indicated by the recent funding of several large collaborative projects by the EU (see for example the SILENV, AQUO and SONIC projects). This paper presents ship radiated noise data measured using a three hydrophone array during a recent sea trial undertaken as part of the SONIC project

    Falling in Acute Mental Health Settings for Older People : Who falls, where, when and why?

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    Copyright: © 2014 Dickinson A et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Falls, slips and trips are a major patient safety concern in hospital settings accounting for 26 per cent of all reported patient safety incidents in England. Mental health conditions and their treatments add further to fall risk but we have little information regarding who falls, where and when within mental health settings. Methods: This paper presents an overview of the pattern of falls by older patients within an in-patient mental health setting in the South of England using routine records completed by staff when a fall occurs. 920 fall reports over three years were analysed, and 7 focus groups were undertaken with ward staff to explore how staff understood falls and their experiences of using the falls reporting system. Results: In terms of diagnosis 40% of fallers had a primary functional diagnosis, 46% an organic mental health diagnosis (14% non-specific diagnosis), average age was 81.7 years (range 59 to 99 years; SD 8.3) and 57% were female. Approximately one quarter, 27%, of falls were observed by staff. Falls were not evenly distributed across either day of week or time of day, with peak times for falls on Tuesday and Saturday and morning (7-8 and 9-10am) and subsidiary peaks between noon and 1pm and early evening (5-6pm). Almost half of falls occurred in private spaces in the ward such as bedrooms, and 42% in public spaces such as sitting rooms. However 60% of falls in public spaces were unseen. Reporting in these settings was problematic for staff and patients were sometimes described as placing themselves on the floor as a consequence of their mental health condition. The average time to first fall was 5 weeks. Conclusions: Routine mapping of falls could be undertaken at ward and organization level and contribute to better understanding of the local factors contributing to falls. Exploring incident report data in focus groups with staff helped us and them to interpret the data and to understand some of the decision making staff engage in everyday when reporting falls.Peer reviewedFinal Published versio

    Modelling and measurement of backscattering from partially water-filled cylindrical shells

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    The backscattering from partially water-filled cylindrical shells has been studied using finite element (FE) analysis and experimental measurements for low to medium frequencies, corresponding to 2 < ka < 30 (where a is the shell outer radius). For a partially-filled shell, filled to three quarters of the inner diameter, backscattering has been investigated numerically as a function of the elevation angle of the incident wave, and in particular as the wave direction changes from horizontal to vertical. Comparisons with fully air-filled and fully water-filled shells indicate that the shell resembles the former when the wave is incident from above and the latter when the wave is incident horizontally. The experiments were performed in a reservoir, using horizontal incidence and wideband Ricker pulses generated by a parametric array. The short duration of the Ricker pulses made it possible to observe a number of returns after the specular return for a shell with a high filling fraction; these included contributions due to S0 waves generated at the front and back walls of the shell, and the back wall return. Inversion of the FE model data enabled the expected waveforms to be predicted; the measurements were in very good agreement with the prediction

    Use of acoustic analogy for marine propeller noise characterisation

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    Being able to predict shipborne noise is of significant importance to international maritime community. Porous Ffowcs-Williams Hawkings acoustic analogy is used with cavitation model by Sauer & Schnerr in order to predict the noise signature of the Potsdam Propeller operating in open water. The radiation pattern is shown to be predominantly affected by a dipole source, in addition to less prominent sources at the propeller plane and in the wake. It is shown that the predicted sound pressure levels depend on the choice of the control surface and grid density. The unsteady RANS method is shown to be capable of capturing the blade harmonic noise components but lacks the ability to deal with the broadband part of the noise spectrum, both cavitation and turbulence induced, if no additional modelling is used

    The influence of turbulence modelling techniques on the predicted cavitation behaviour on a NACA0009 foil

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    The work presented here forms part of a project focusing on the development of cost-effective measures of classifying the noise levels from ship propellers with the use of numerical techniques available in OpenFOAM software. It is also related to the on-going research within the Faculty of Engineering and the Environment at the University of Southampton, looking at underwater noise of tidal turbines. Ultimately, the aim of the complete study is to enable the assessment of the environmental impact of a ship on the marine ecosystems. In this work a set of results from numerical experiments applied to the NACA0009 foil is presented in the context of quantifying the noise levels produced by a cavitating body in a uniform flow. The simulations utilise both URANS and LES methods and provide a means of characterising the differences between the observed flow patterns from the cavitation modelling point of view. In particular, the interactions of the cavitation phenomena with the turbulence, both modelled and resolved, are studied. Furthermore, an overview of how the considered cavitation models may be used for the purpose of noise prediction is give

    Mechanisms of pelvic floor muscle function and the effect on the urethra during a cough

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    Background: Current measurement tools have difficulty identifying the automaticphysiologic processes maintaining continence, and many questions still remainabout pelvic floor muscle (PFM) function during automatic events.Objective: To perform a feasibility study to characterise the displacement, velocity,and acceleration of the PFM and the urethra during a cough.Design, setting, and participants: A volunteer convenience sample of 23 continentwomen and 9 women with stress urinary incontinence (SUI) from the generalcommunity of San Francisco Bay Area was studied.Measurements: Methods included perineal ultrasound imaging, motion trackingof the urogenital structures, and digital vaginal examination. Statistical analysisused one-tailed unpaired student t tests, and Welch’s correction was applied whenvariances were unequal.Results and limitations: The cough reflex activated the PFM of continent women tocompress the urogenital structures towards the pubic symphysis, which wasabsent in women with SUI. The maximum accelerations that acted on the PFMduring a cough were generally more similar than the velocities and displacements.The urethras of women with SUI were exposed to uncontrolled transverse accelerationand were displaced more than twice as far ( p = 0.0002), with almost twicethe velocity ( p = 0.0015) of the urethras of continent women. Caution regardingthe generalisability of this study is warranted due to the small number of women inthe SUI group and the significant difference in parity between groups.Conclusions: During a cough, normal PFM function produces timely compressionof the pelvic floor and additional external support to the urethra, reducing displacement,velocity, and acceleration. In women with SUI, who have weakerurethral attachments, this shortening contraction does not occur; consequently,the urethras of women with SUI move further and faster for a longer duratio

    Multi-scale modelling of cavitation-induced pressure around the delft twist 11 hydrofoil

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    A hybrid Lagrangian-Eulerian cavitation model based on the Schnerr-Sauer mass-transfer formulation is developed and then applied to study the flow around the Delft Twist 11 hydrofoil. The model uses volume-of-fluid approach to resolve large cavities and uses an interface reconstruction algorithm to identify vapour structures smaller than a grid-related threshold. These are then transferred to a Lagrangian framework and convected as particles acting as point noise sources. The underlying volume-of-fluid (VOF) model is shown to be in qualitatively good agreement with the experiment although it is found to under-predict the extent of cavitation. The combined model shows a substantial improvement in the prediction of near-field pressure fluctuations by accounting for the broadband contribution of bubbles smaller than the Eulerian grid size. In the pressure fluctuation spectra this is seen as a plateau extending to over a kilohertz beyond the low-frequency harmonics associated with the shedding frequency

    Protective effi cacy of prolonged co-trimoxazole prophylaxis in HIV-exposed children up to age 4 years for the prevention of malaria in Uganda: a randomised controlled open-label trial

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    Background WHO recommends daily co-trimoxazole for children born to HIV-infected mothers from 6 weeks of age until breastfeeding cessation and exclusion of HIV infection. We have previously reported on the eff ectiveness of continuation of co-trimoxazole prophylaxis up to age 2 years in these children. We assessed the protective effi cacy and safety of prolonging co-trimoxazole prophylaxis until age 4 years in HIV-exposed children. Methods We undertook an open-label randomised controlled trial alongside two observational cohorts in eastern Uganda, an area with high HIV prevalence, malaria transmission intensity, and antifolate resistance. We enrolled HIVexposed infants between 6 weeks and 9 months of age and prescribed them daily co-trimoxazole until breastfeeding cessation and HIV-status confi rmation. At the end of breastfeeding, children who remained HIV-uninfected were randomly assigned (1:1) to discontinue co-trimoxazole or to continue taking it up to age 2 years. At age 2 years, children who continued co-trimoxazole prophylaxis were randomly assigned (1:1) to discontinue or continue prophylaxis from age 2 years to age 4 years. The primary outcome was incidence of malaria (defi ned as the number of treatments for new episodes of malaria diagnosed with positive thick smear) at age 4 years. For additional comparisons, we observed 48 HIV-infected children who took continuous co-trimoxazole prophylaxis and 100 HIV-unexposed uninfected children who never received prophylaxis. We measured grade 3 and 4 serious adverse events and hospital admissions. All children were followed up to age 5 years and all analyses were by intention to treat. This study is registered with ClinicalTrials.gov, number NCT00527800. Findings 203 HIV-exposed infants were enrolled between Aug 10, 2007, and March 28, 2008. After breastfeeding ended, 185 children were not infected with HIV and were randomly assigned to stop (n=87) or continue (n=98) co-trimoxazole up to age 2 years. At age 2 years, 91 HIV-exposed children who had remained on co-trimoxazole prophylaxis were randomly assigned to discontinue (n=46) or continue (n=45) co-trimoxazole from age 2 years to age 4 years. We recorded 243 malaria episodes (2·91 per person-years) in the 45 HIV-exposed children assigned to continue cotrimoxazole until age 4 years compared with 503 episodes (5·60 per person-years) in the 46 children assigned to stop co-trimoxazole at age 2 years (incidence rate ratio 0·53, 95% CI 0·39–0·71; p<0·0001). There was no evidence of malaria incidence rebound in the year after discontinuation of co-trimoxazole in the HIV-exposed children who stopped co-trimoxazole at age 2 years, but incidence increased signifi cantly in HIV-exposed children who stopped co-trimoxazole at age 4 years (odds ratio 1·78, 95% CI 1·19–2·66; p=0·005). Incidence of grade 3 or 4 serious adverse events, hospital admissions, or deaths did not signifi cantly diff er between HIV-exposed, HIV-unexposed, and HIV-infected children. Interpretation Continuation of co-trimoxazole prophylaxis up to 4 years of age seems safe and effi cacious to protect HIV-exposed children living in malaria-endemic areas

    The contribution to anthropogenic noise from marine aggregate extraction operation in UK waters

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    As of 2009, there were 75 licensed areas within UK waters for marine aggregate extraction. Each year, around 20 million tonnes of sand and gravel are extracted from these areas for use in the construction and building industry1. Extraction of marine aggregate has the potential to generate noise, and if at sufficient levels, this could have a negative impact on marine species in or around the dredging area. However, measurement of the noise generated during marine aggregate extraction has been limited, particularly in UK waters. The most extensive measurements were undertaken in the Beaufort Sea during oil exploration in the 1980s2,3. Other measurements around Sakhalin Island have been reported in the literature, which were compared by Ainslie et al4 to other vessels including the Overseas Harriette5. This paper presents the results of underwater noise measurements for six different dredgers measured in three locations around the UK, with aggregate type varying from sand to coarse gravel. From the measurements of radiated noise for dredgers under normal operation an estimate is made of the long term contributions to ambient noise levels from typical dredgers under normal operation, the contribution to the overall ambient noise budget, and the cumulative Sound Exposure Level for receptors in the vicinity

    Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children

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    BACKGROUND: Artemisinin combination therapy has become the standard of care for uncomplicated malaria in most of Africa. However, there is limited data on the safety and tolerability of these drugs, especially in young children and patients co-infected with HIV. METHODS: A longitudinal, randomized controlled trial was conducted in a cohort of HIV-infected and uninfected children aged 4-22 months in Tororo, Uganda. Participants were randomized to treatment with artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine (DP) upon diagnosis of their first episode of uncomplicated malaria and received the same regimen for all subsequent episodes. Participants were actively monitored for adverse events for 28 days and then passively for up to 63 days after treatment. This study was registered in ClinicalTrials.gov (registration # NCT00527800). RESULTS: A total of 122 children were randomized to AL and 124 to DP, resulting in 412 and 425 treatments, respectively. Most adverse events were rare, with only cough, diarrhoea, vomiting, and anaemia occurring in more than 1% of treatments. There were no differences in the risk of these events between treatment groups. Younger age was associated with an increased risk of diarrhoea in both the AL and DP treatment arms. Retreatment for malaria within 17-28 days was associated with an increased risk of vomiting in the DP treatment arm (HR = 6.47, 95% CI 2.31-18.1, p < 0.001). There was no increase in the risk of diarrhoea or vomiting for children who were HIV-infected or on concomitant therapy with antiretrovirals or trimethoprim-sulphamethoxazole prophylaxis. CONCLUSION: Both AL and DP were safe and well tolerated for the treatment of uncomplicated malaria in young HIV-infected and uninfected children. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00527800; http://clinicaltrials.gov/ct2/show/NCT00527800
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